Assistant Director - Developmental Therapeutics Core (Sr Research Associate

Department

CLP - DTC

RES/

The Developmental Therapeutics Core (DTC) of Northwestern University has an immediate opening for a Sr Research Associate who will serve as the Assistant Director - Developmental Therapeutics Core providing scientific, operational, financial, and regulatory leadership and to lead the continued growth of this highly productive, in-demand translational research resource.

The DTC is a core facility within the Chemistry of Life Processes Institute (CLP) at Northwestern University. From involvement in landmark Alzheimer's studies to revolutionary new treatments for cancer, Parkinson's disease, cardiovascular disease, and addiction, DTC plays a critical role in advanced biomedical research and the translation of novel therapeutics, diagnostics, and medical devices.

The Core provides a comprehensive suite of fee-for-service support services including in vitro and in vivo assessment of drug activity and mechanism of action, efficacy studies, pharmacokinetics/pharmacodynamics (PK/PD), biodistribution, toxicology, biomarker analyses, imaging-based studies, microbiome-related research, patient-derived xenograft (PDX), orthotopic, syngeneic and humanized animal models, device evaluation studies, scientific consultation, project management, and clinical trial support in a fast-paced translational research environment.

A complete application should include:

• Cover Letter
• Curriculum Vitae
• Summary of Research Accomplishments
• Contact information for three references (name, postal and email addresses, phone number)

This is 3-year term position. Opportunity for renewal will be based on performance and available funding

• Communicate and collaborate with principal investigators, industry sponsors, students, postdoctoral fellows, and research staff to develop study objectives, experimental designs, timelines, budgets, and translational research strategies
• Serve as the primary scientific and operational resource for the Core and independently manage multiple complex projects and stakeholders with minimal supervision.
• In coordination with the Faculty Advisory Board, develop and implement a robust strategic plan for the facility, including scientific growth, financial sustainability, operational efficiency, and expansion of services.
• Organize, prepare materials for, and present Core utilization metrics, financial performance, scientific accomplishments, strategic initiatives, and recommendations during biannual Advisory Board meetings.
• Hire, train, supervise, mentor, and evaluate DTC technical staff while fostering professional development and maintaining a collaborative research environment.
• Write and manage blanket IACUC protocols and amendments and oversee staff compliance with animal welfare, biosafety, human research safety, and regulatory requirements.
• Work with the Northwestern IACUC, Center for Comparative Medicine, and other institutional regulatory offices to ensure that animal care and handling meet the highest possible standards.
• Provide scientific leadership in the design, execution, troubleshooting, interpretation, and reporting of complex in vitro and in vivo studies that meet the highest standards of rigor, reproducibility, and translational relevance.
• Provide scientific consultation regarding study design, power analysis, endpoint selection, animal model selection, statistical considerations, and data interpretation.
• Perform and oversee data analyses and preparation of final study reports for academic, government, foundation, and industry-sponsored projects.
• Ensure that data records, analyses, and reports meet the highest standards for transparency, reproducibility, and scientific integrity.
• Develop project scopes of work, quotations, budgets, and timelines and oversee customer billing and recharge activities in collaboration with the CLP business office.
• Develop annual reports, cost studies, utilization analyses, recharge rate recommendations, budget forecasts, and operational reports required for long-term financial sustainability.
• Oversee marketing and outreach activities and develop internal and external collaborations and partnerships to increase utilization, revenue generation, and scientific impact.
• Assist investigators with grant applications, letters of support, manuscript preparation, and translational research planning.
• Represent the Core at institutional seminars, scientific meetings, conferences, and external collaborations.
• Create SOPs and ensure that these SOPs are accurately reflected in executed studies and projects.

Performs other duties as assigned.

• PhD in biological sciences, pharmacology, biomedical sciences, or a related discipline
• Minimum 10 years of relevant research associate, laboratory, translational research, biotechnology, pharmaceutical, CRO, or core facility experience.

• Cell culture, animal handling, microscopic analysis, and aseptic method.
• Euthanasia and harvesting/collection of organs…