Team Lead, Statistical Programming, Oncology; Director

About Astellas

Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. Learn more at

We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.

As a senior statistician, data scientist or clinical programmer, the position has a dual purpose: manage 4+ direct reports and have a major influence on the leadership and technical capabilities of the department. The role can act as Global Statistical Lead (GSTATL), Global Programmer Lead (GPROGL), Real World Data Scientist Lead (RWDSL), Lead Product Statistician (LPS), Statistical Biomarker Lead (SBL) or as a Regional/site Head.

The position is responsible for the optimal development and assignment of reports to Astellas asset teams, study teams or deliverables teams, supporting senior management with decision making at the asset and portfolio level, representing Astellas on statistical matters related to clinical data, RWD, Biomarkers, PROs, PK/PD analysis or methodology at meetings with regulatory authorities and HTAs.

• Advises asset teams on challenging statistical/epidemiological design, analysis and decision‑making issues for interventional and non-interventional studies.
• Explains how RWD and clinical trial post‑hoc analyses can support drug development, pricing submissions and the growth strategy.
• Describes how omics and biomarkers can support drug development and the BOLD objectives.
• Provides programming support for all stakeholders globally, performs and supervises modeling and simulations, and leverages external experts for clinical development issues.
• Provides oversight on statistical/scientific/programming matters for meetings with regulatory authorities, HTAs, key opinion leaders and similar experts.
• Reviews key project‑level documents.
• Participates in due diligence activities, external initiatives or working groups.
• Presents and defends complex solutions to governance committees (KACHI, PRC, MA‑C, EC), key stakeholders, or regulatory bodies in an impactful manner.
• Stays at the cutting edge of methodology development in statistics, epidemiology, regulatory and HTA guidelines, and industry trends relevant to the primary focus of interest.
• Ensures efficient and innovative programming approaches for each deliverable.
• Researches, creates, validates, implements, and teaches complex methodologies to keep the department at the forefront of innovative drug development.

• Supervises (first line manager) 4+ direct reports.
• Assists with recruitment, development/career management and retention of staff.
• Oversees adherence to timelines, standards, and processes for work assigned to team members.
• Ensures compliance of direct reports with Astellas policies and procedures.

• Challenges and influences peers and senior managers inside and outside Quantitative Sciences and Evidence Generation on best practice.
• Develops and maintains relationships with peers and key leaders as a member of external industry or professional organizations.
• Uses the position to advance Astellas’ mission through high‑quality statistical programming work, ensuring the team stays current with global regulatory changes.
• Contributes to ensuring Astellas leads in recruitment, training, professional development and retention of statistical programming personnel.
• Partners with SRS LT to set short‑ and long‑term strategic direction for the programming function.
• Partners with programming teams at other Astellas sites to ensure global consistency and efficient resource utilization.

• Bachelor’s or master’s in statistics, mathematics, or a related field.
• 12+…