Project Manager - Cell & Gene Therapy; Sponsor Dedicated - US Remote; Preference Los Ange

Project Manager I – Cell & Gene Therapy (Sponsor Dedicated – US Remote; Preference for Los Angeles, CA)

Syneos Health is a leading fully-integrated life sciences services organization built to accelerate customer success. We partner with innovators at every point across the drug development and commercialization continuum, helping them navigate complexity, anticipate change and accelerate progress.

Location: strongly prefer candidates located near our sponsor's Los Angeles office (near Westwood neighborhood/UCLA campus).

Job Responsibilities

• Act as a sponsor-facing project manager, ensuring the successful execution of assigned CAR‑T and gene therapy trials from startup through closeout.
• Lead or support study start‑up, site activation, and enrollment, working closely with site monitors, regulatory teams, and contracts personnel.
• Serve as a key point of contact across internal (CRO) and sponsor teams, facilitating regular communications, status reporting, and governance updates.
• Coordinate with cross‑functional stakeholders to ensure timelines, budgets, and milestones are met, particularly in complex, high‑touch studies.
• Track and manage protocol compliance, CAPAs, and site‑level quality indicators; support resolution of audit findings.
• Ensure inspection readiness and regulatory compliance by overseeing TMF maintenance, data accuracy, and documentation completeness.
• Manage or contribute to the tracking of low‑stability endpoint samples and IP‑related processes, ensuring timely lab delivery and site support.
• Assist with risk identification and mitigation planning, while continuously optimizing trial execution processes.

• 2-4 years of clinical trial experience, preferably in a CRO setting, with a focus on oncology, rare disease, or gene-modified cell therapy trials.
• Prior involvement in CAR‑T or other cell therapy studies is highly desirable.
• Strong familiarity with GCP/ICH guidelines, FDA/EMA regulations, and inspection‑readiness standards.
• Experience working in sponsor‑dedicated or embedded roles within a CRO is a plus.
• Proficiency in clinical systems (CTMS, EDC, eTMF) and project management tools.
• Confident in leading sponsor calls, presenting KPIs, and contributing to operational governance.
• Bachelor's degree in a relevant field (Life Sciences, Nursing, Pharmacy, etc.) or equivalent work experience.
• Comfortable with remote work but agreeable to occasional in‑person collaboration in Los Angeles.

This role offers the opportunity to do more than manage clinical trials – it's a chance to be at the center of some of the most promising therapeutic advancements in the world. You'll play a critical role in accelerating the development of treatments that could change patients' lives forever.

If you're looking to grow your career while making a real‑world impact, we invite you to apply and join a mission that matters.

At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality‑of‑life balance. The benefits for this position may include a company car or car allowance, health benefits to include medical, dental and vision, company match 401(k), eligibility to participate in Employee Stock Purchase Plan, eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time.

Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state and municipal paid sick time requirements.

The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate's qualifications, skills, competencies, and proficiency for the role.

Additional Information:
Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above.

Further, nothing contained herein should be construed to create an employment contract. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.